| 主权项 |
1. A compound having the Formula (I):wherein,
A and B are independently CR3 or N; ring R is selected from Formula (i) to (iii): L is selected from —NR8C(O)—, —C(O)NR8— and —NR8CH2—; X is CR or N where R is selected from hydrogen, halogen or substituted or unsubstituted alkyl; R1, which may be same or different at each occurrence, is independently selected from halogen, cyano, hydroxyl, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkoxy and substituted or unsubstituted haloalkoxy; R2, which may be same or different at each occurrence, is independently selected from halogen, cyano, nitro, hydroxyl, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted haloalkoxy, —NR9R10 and substituted or unsubstituted cycloalkyl, —COOR8 and —CONR9R10; each of R3 is independently selected from hydrogen, halogen and substituted or unsubstituted alkyl; R4 and R5, which may be same or different and are independently selected from hydrogen, hydroxyl, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted cycloalkyl and —NR9R10; or R4 and R5 together with the carbon atom to which they are attached form oxo (C═O); one of R6 and R7 is substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted hydroxyalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted alkoxyalkyl and the other is selected from hydrogen, hydroxyl, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted hydroxyalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted alkoxyalkyl, —NR9R10, substituted or unsubstituted cycloalkyl, —COOR8 and —CONR9R10; or R6 and R7 together with the carbon atom to which they are attached may form substituted or unsubstituted 3 to 7 membered carbocyclic ring or 4 to 7 membered heterocyclic ring; R8 is hydrogen or substituted or unsubstituted alkyl; R9 and R10, which may be same or different, are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, and substituted or unsubstituted cycloalkyl; or R9 and R10, together with the nitrogen atom to which they are attached, may form a substituted or unsubstituted, saturated or unsaturated 5 to 7 membered cyclic ring, wherein the unsaturated cyclic ring may have one or two double bonds; Ra and Rb, which may be same or different and are independently selected from hydrogen, cyano, substituted or unsubstituted hydroxyalkyl, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted haloalkoxy, substituted or unsubstituted cycloalkyl, —NR9R10, —COOR8 and —CONH2; ‘n’ is an integer ranging from 1 to 3, both inclusive; and p′ is an integer ranging from 0 to 2, both inclusive; or a pharmaceutically acceptable salt thereof. |
