发明名称 IN VITRO ORAL BIOFILM MODELS OF INTERDENTAL SPACES AND USES
摘要 Disclosed is an in vitro oral biofilm model of interdental spaces including: a support, and a plurality of substratum pairs attached to the support, wherein an oral biofilm is capable of forming on the substratum pairs, wherein the substratum pairs each include a first member and a second member, and wherein the first member and the second member of each substratum pair are arranged to form a space interval between the first member and second member. Methods for assessing the formation of oral biofilms using the in vitro oral biofilm model and methods for testing agents, such as oral compositions, on biofilm reduction using the present model are also provided.
申请公布号 WO2016076842(A1) 申请公布日期 2016.05.19
申请号 WO2014US65094 申请日期 2014.11.11
申请人 COLGATE-PALMOLIVE COMPANY 发明人 STETTLER, HANS;RUSSO, AMY
分类号 C12M1/12;C12Q1/18 主分类号 C12M1/12
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