| 摘要 |
The present invention provides a nucleoside phosphoramidate derivative and an application thereof, which is specifically a compound represented by formula I, or a pharmaceutically acceptable acidic salt, a solvate or a hydrate thereof. R1 is C1-4 alkyl; R2 is any substituted phenyl or naphthyl, and a substituent group thereof is selected from C1-4 alkyl and C1-4 alkoxy; and R3 is amino acid acyl or peptide acyl. The compound in the present invention can be used to prepare a drug for preventing or treating mammalian infectious diseases, and especially used to prepare drugs for preventing or treating hepatitis c, liver cirrhosis, and a liver cancer. |
