发明名称 ANTIBODY SPECIFICALLY BINDING TO INSULIN-LIKE GROWTH FACTOR-1
摘要 Isolated antibodies that specifically bind to an epitope comprised in the stretch of amino acids ranging from amino acid 76 to amino acid 84 of human insulin-like growth factor-1 precursor (SEQ ID NO:1). Use of the novel antibodies for the sensitive and specific detection of insulin-like growth factor-1, in some embodiments while in the presence of high excess concentration of insulin-like growth factor-2, for example in a bodily fluid sample.
申请公布号 US2016137728(A1) 申请公布日期 2016.05.19
申请号 US201615003988 申请日期 2016.01.22
申请人 Roche Diagnostics Operations, Inc. 发明人 Andres Herbert;Duefel Hartmut;Gerg Michael;Kowalewsky Frank;Scholz Christian;Schraeml Michael
分类号 C07K16/22 主分类号 C07K16/22
代理机构 代理人
主权项 1. An antibody which specifically binds an epitope comprised within amino acids 77 to 84 (SEQ ID NO.4) of insulin-like growth factor-1 precursor (SEQ ID NO.1).
地址 Indianapolis IN US