PEPTIDES WITH ENHANCED STABILITY AND THEIR USE IN METHODS FOR TREATING DISEASES

摘要

The invention provides peptides that are useful for treating or preventing, or preventing the progression of a disorder associated with aberrant TDF polypeptide or TDFRP compound target molecule expression or activity, for example a kidney disease or disorder, in a subject. The invention also provides methods of treating a subject having a disorder associated with aberrant TDF polypeptide or TDFRP compound target molecule expression or activity, such as a kidney disease or disorder, comprising administering to the subject an effective amount of the peptides of the invention.

主权项

1. A method of treating a subject having a disease or disorder, or delaying the progression of a disease or a disorder in a subject, the method comprising administering to the subject an effective amount of a peptide comprising one or more of SEQ ID NO:1-72,
wherein the disease or disorder is a disease or disorder associated with aberrant TDF polypeptide or TDFRP compound target molecule expression or activity, thereby treating the disorder associated with aberrant TDF polypeptide or TDFRP compound target molecule expression or activity in the subject.