| 发明名称 |
COMBINATION THERAPY USING 1-AMINOCYCLOHEXANE DERIVATIVES AND ACETYLCHOLINESTERASE INHIBITORS |
| 摘要 |
The invention relates to a novel drug combination therapy useful in the treatment of dementia comprising administering a 1-aminocyclohexane derivative such as memantine and an acetylcholinesterase inhibitor (AChEI) such as donepezil. |
| 申请公布号 |
US2016136144(A1) |
申请公布日期 |
2016.05.19 |
| 申请号 |
US201615008646 |
申请日期 |
2016.01.28 |
| 申请人 |
MERZ PHARMA GmbH & CO. KGaA |
发明人 |
MOEBIUS Hans-Joerg |
| 分类号 |
A61K31/445;A61K9/00;A61K9/20;A61K31/13 |
主分类号 |
A61K31/445 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating Alzheimer's disease in a subject in need thereof, comprising administration of a 1-aminocyclohexane derivative selected from memantine, and salts thereof, and an acetylcholinesterase inhibitor (AChEI) selected from donepezil, and salts thereof, wherein the combined treatment with the 1-aminocyclohexane derivative and the acetylcholinesterase inhibitor (AChEI) provides cognitive improvement. |
| 地址 |
Frankfurt am MAIN DE |
