发明名称 METHOD FOR ISOLATING SPECIFIC GENOMIC REGION USING MOLECULE BINDING SPECIFICALLY TO ENDOGENOUS DNA SEQUENCE
摘要 Provided is a method comprising (A) fragmenting genomic DNA in a state where the interaction of the genomic DNA and molecules interacting therewith is maintained, and(B) bringing genomic DNA into contact with an exogenous molecule capable of binding to a specific endogenous DNA sequence in the genomic DNA.;According to the method, with the use of an endogenous DNA sequence present inside or in the vicinity of a target genomic region in cells to be analyzed, any genomic region can be specifically isolated in a state where the interaction of the genomic region and molecules interacting therewith is maintained, without the need of inserting a recognition sequence of an exogenous DNA-binding molecule into the vicinity of the target genomic region in the cells to be analyzed.
申请公布号 US2016138081(A1) 申请公布日期 2016.05.19
申请号 US201314767068 申请日期 2013.09.06
申请人 OSAKA UNIVERSITY 发明人 FUJII Hodaka;FUJITA Toshitsugu
分类号 C12Q1/68;G01N33/53 主分类号 C12Q1/68
代理机构 代理人
主权项
地址 Suita-shi, Osaka JP