Non-Regular Electrical Stimulation Patterns Designed with a Cost Function for Treating Neurological Disorders

摘要

Systems and methods for stimulation of neurological tissue generate stimulation trains with temporal patterns of stimulation, in which the interval between electrical pulses (the inter-pulse intervals) changes or varies over time. Compared to conventional continuous, high rate pulse trains having regular (i.e., constant) inter-pulse intervals, the non-regular (i.e., not constant) pulse patterns or trains that embody features of the invention provide a lower average frequency.

主权项

1. A neural stimulation device comprising:
a pulse generator transmitting temporal patterns of stimulation to neurological tissue through at least one electrode operatively coupled with the pulse generator, said temporal patterns including: a first temporal pattern having a first non-regular pulse train comprising a plurality of pulses having differing inter-pulse intervals between pulses to treat a neurological condition, said first temporal pattern adapted from applying a first model-based optimization technique; and optional subsequent temporal patterns having a subsequent non-regular pulse train comprising a plurality of pulses having non-regular inter-pulse intervals between the pulses to treat a neurological condition, the subsequent temporal patterns adapted from applying a model-based optimization technique.