发明名称 |
ANTI-ENDOGLIN ANTIBODIES AND USES THEREOF |
摘要 |
The present application relates to compositions of humanized and deimmunized anti-endoglin antibodies and antigen-binding fragments thereof. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to anti-endoglin antibodies which inhibit or treat fibrosis. |
申请公布号 |
WO2016077451(A1) |
申请公布日期 |
2016.05.19 |
申请号 |
WO2015US60136 |
申请日期 |
2015.11.11 |
申请人 |
TRACON PHARMACEUTICALS, INC. |
发明人 |
THEUER, CHARLES |
分类号 |
A61K39/395;A61P1/16;A61P11/00;A61P13/12 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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