发明名称 |
Formulations of deoxycholic acid and salts thereof |
摘要 |
The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5. |
申请公布号 |
AU2016202661(A1) |
申请公布日期 |
2016.05.19 |
申请号 |
AU20160202661 |
申请日期 |
2016.04.27 |
申请人 |
KYTHERA BIOPHARMACEUTICALS, INC. |
发明人 |
HODGE, ROBERT EMIL;WEBSTER, JEFFREY DOUGLAS;MORIARTY, ROBERT M. |
分类号 |
A61K9/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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