发明名称 2-AMINO-6-(DIFLUOROMETHYL)- 5,5-DIFLUORO-6-PHENYL-3,4,5,6-TETRAHYDROPYRIDINES AS BACE1 INHIBITORS
摘要 The present invention is directed to compounds of formula (I) which are inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of Αβ deposits is beneficial such as Alzheimer's disease.
申请公布号 WO2016075063(A1) 申请公布日期 2016.05.19
申请号 WO2015EP76015 申请日期 2015.11.09
申请人 H. LUNDBECK A/S 发明人 JUHL, KARSTEN;TAGMOSE, LENA;MARIGO, MAURO
分类号 C07D401/12;A61K31/4439;A61K31/444;A61K31/497;A61K31/506;A61P25/28;C07D413/12;C07D417/12 主分类号 C07D401/12
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