发明名称 デオキシコール酸およびその塩類の製剤
摘要 The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
申请公布号 JP5919597(B2) 申请公布日期 2016.05.18
申请号 JP20140527128 申请日期 2011.08.23
申请人 キテラ バイオファーマシューティカルズ,インコーポレイテッド 发明人 ホッジ,ロバート エミル;ウェブスター,ジェフリー ダグラス;モリアーティ,ロバート エム.
分类号 A61K31/575;A61K9/08;A61K47/10;A61P3/00 主分类号 A61K31/575
代理机构 代理人
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