摘要 |
Genetic characterisation of closely related inbreds is at present only possible by means of whole genome sequencing. This is however a time-consuming process. The invention addresses the need for a method to differentiate between closely related substrains of inbreds. The method involves analysis of at least two tandem repeat loci per chromosome. Said tandem repeat loci are characterised by high mutation rates. The amplified fragments are subsequently used to determine the alleles that are present at each amplified locus within the DNA sample. |