Local delivery with a balloon covered by a cage

摘要

A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.

主权项

1. An agent delivery assembly comprising:
an inflatable balloon having an exterior working length between a distal section and a proximal section, wherein the inflatable balloon includes an uninflated state and a fully inflated state; and a self-crimping stent-like structure having a distal end and a proximal end, wherein the self-crimping stent-like structure includes an opened state and a small diameter state, wherein the self-crimping stent-like structure substantially covers the exterior working length of the inflatable balloon with the distal end being distal to the distal section and the proximal end being proximal to the proximal section, wherein the self-crimping stent-like structure is self-collapsible from the opened state when the inflatable balloon is in the fully inflated state to the small diameter state when the inflatable balloon is in the uninflated state and is removable from a lumen, wherein the self-crimping stent-like structure separates the inflatable balloon from a lumen wall when the inflatable balloon is in the fully inflated state within the lumen, and wherein the self-crimping stent-like structure does not damage a target tissue within the lumen when the self-crimping stent-like structure is in contact with the target tissue and the inflatable balloon is in the fully inflated state within the lumen.