| 发明名称 | Lipid vesicle compositions and methods of use | ||
| 摘要 | The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar vesicles may comprise prophylactic, therapeutic and/or diagnostic agents. | ||
| 申请公布号 | US9339462(B2) | 申请公布日期 | 2016.05.17 |
| 申请号 | US201414581004 | 申请日期 | 2014.12.23 |
| 申请人 | Massachusetts Institute of Technology | 发明人 | Irvine Darrell J.;Moon Jaehyun |
| 分类号 | A61K9/127;A61K38/20;A61K45/06;A61K39/21;A61K39/39;C07K14/005;A61K39/12;A61K39/35;C07K16/28;A61K39/395;A61K39/00 | 主分类号 | A61K9/127 |
| 代理机构 | Wolf, Greenfield & Sacks, P.C. | 代理人 | Wolf, Greenfield & Sacks, P.C. |
| 主权项 | 1. A multilamellar lipid vesicle having at least two lipid bilayers covalently crosslinked to each other through headgroups that react with covalent crosslinkers to form covalent crosslinks between the at least two lipid bilayers, wherein the multilamellar lipid vesicle comprises an immunomodulatory agent. | ||
| 地址 | Cambridge MA US | ||