| 发明名称 | Inhibitors of protein tyrosine phosphatases | ||
| 摘要 | Novel protein tyrosine phosphatase (PTP) inhibitor compounds synthesized from phosphonodifluoromethyl phenylalanine (F2Pmp) are provided. Use of these compounds for inhibiting a PTP enzyme (such as PTP-MEG2), as well as treating a disease, disorder, or condition associated with inappropriate activity of a PTP (such as type 2 diabetes), is also provided. | ||
| 申请公布号 | US9340574(B2) | 申请公布日期 | 2016.05.17 |
| 申请号 | US201314432511 | 申请日期 | 2013.10.03 |
| 申请人 | Indiana University Research and Technology Corporation | 发明人 | Zhang Zhong-Yin;Zhang Sheng |
| 分类号 | A61K38/06;A61K38/07;C07K5/087;C07F9/655;C07F9/6558;C07F9/38;C07K5/065;A61K38/00 | 主分类号 | A61K38/06 |
| 代理机构 | Stinson Leonard Street LLP | 代理人 | Stinson Leonard Street LLP |
| 主权项 | 1. A compound of Formula A:or a therapeutically suitable prodrug thereof or a therapeutically suitable salt thereof, wherein R1, R2, and R3 are the same or different and each individually is an acyl group of a carboxylic acid. | ||
| 地址 | Indianapolis IN US | ||