| 发明名称 | Method for vector delivery | ||
| 摘要 | Provided is a lentiviral vector for delivery to the brain for use in treating a neurological condition, wherein the lentiviral vector is delivered directly to the brain by delivering the lentiviral vector via six or fewer tracts per hemisphere, at a single deposit point per tract. | ||
| 申请公布号 | US9339512(B2) | 申请公布日期 | 2016.05.17 |
| 申请号 | US201313893920 | 申请日期 | 2013.05.14 |
| 申请人 | Oxford BioMedica (UK) Limited | 发明人 | Widdowson Peter;Ralph Scott;Mitrophanous Kyriacos A. |
| 分类号 | A61K31/70;C12N15/63;A61M31/00;A61K31/711;C12N15/86;A61M5/178;A61K48/00 | 主分类号 | A61K31/70 |
| 代理机构 | Grimes & Yvon LLP | 代理人 | Grimes & Yvon LLP |
| 主权项 | 1. A method for delivering a lentiviral vector to the putamen of a primate subject, wherein the method comprises directly administering to the putamen of the primate subject via continuous infusion, using a cannula with a bore equivalent to or narrower than 28 gauge, a composition comprising a lentiviral vector, wherein the composition is delivered at a flow rate of at least 2 μL/min. | ||
| 地址 | Oxford GB | ||