T cell apoptosis inducer and method therefore

摘要

An inducer of T cell apoptosis and a health food for inducing T cell apoptosis comprising as an active ingredient of a lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium are disclosed. Particularly preferred lactic acid bacteria belonging to the genus Lactobacillus or the genus Bifidobacterium are Lactobacillus acidophilus L-92 (FERM BP-4981), Lactobacillus amylovorus CP1750 (FERM BP-10532), Bifidobacterium catenulatum CP2829 (FERM BP-10533) and Bifidobacterium longum CP760 (FERM BP-10531). The inducer of T cell apoptosis of the invention is useful in the prevention and cure of a disease such as an organ-specific autoimmune disease or type I allergy.

主权项

1. A method for inducing T cell apoptosis comprising:
administering to a subject in need thereof a biologically pure lactic acid bacterium belonging to the genus Lactobacillus or the genus Bifidobacterium as an active ingredient and a carrier, wherein the biologically pure lactic acid bacterium is selected from the group consisting of Lactobacillus acidophilus strain FERM BP-4981, Lactobacillus amylovorus strain FERM BP-10532, Bifidobacterium catenulatum strain FERM BP-10533 and Bifidobacterium longum strain FERM BP-10531.