发明名称 |
1,2,4-TRIAZOLO[4,3-a]PYRIDINE COMPOUNDS AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
摘要 |
The present invention relates to novel 1,2,4-triazolo[4,3-a]pyridine compounds of Formula (I) as positive allosteric modulators (PAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of mGluR2 subtype disorders. |
申请公布号 |
PH12016500312(A1) |
申请公布日期 |
2016.05.16 |
申请号 |
PH2012120165003 |
申请日期 |
2016.02.16 |
申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
CID-NUNEZ, JOSE, MARIA;TRABANCO-SUAREZ, ANDRES, AVELINO;LAVREYSEN, HILDE;CEUSTERS, MARC ANDRE |
分类号 |
A61K31/437;C07D471/04 |
主分类号 |
A61K31/437 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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