GENOMIC-ANALYSIS APPARATUS, GENOMIC-ANALYSIS METHOD, AND GENOMIC-ANALYSIS PROGRAM

摘要

PROBLEM TO BE SOLVED: To provide a technique which enables identification of the responsible mutation related to a particular hereditary phenotype with high accuracy.SOLUTION: A genomic-analysis apparatus related to the one aspect of the invention comprises: a candidate mutation evaluating part which calculates evaluation values for evaluating specificity of each candidate mutation by obtaining each genome base sequence of a target organism with a particular hereditary phenotype and a plurality of control organisms without the hereditary phenotype, calculating the different degree of the mutation part between the target organism and each control organism, and the different degrees of the mutation parts among a plurality of control organisms, for every partial genome base sequence comprising the candidate mutation which serves as a candidate of the responsible mutation of the hereditary phenotype, and examining whether the difference between both calculated different degrees is significant; and an output control part which outputs the result of the examination in the condition that the order of each candidate mutation can be identified based on the evaluation values.SELECTED DRAWING: Figure 4