发明名称 INHIBITORS OF INFLUENZA VIRUSES REPLICATION.
摘要 Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (I) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.
申请公布号 MX339149(B) 申请公布日期 2016.05.13
申请号 MX20140001067 申请日期 2012.08.01
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 HONGBO DENG;PAUL S. CHARIFSON;MICHAEL P. CLARK;UPUL K. BANDARAGE;RANDY S. BETHIEL;MICHAEL J. BOYD;IOANA DAVIES;JOHN P. DUFFY;LUC J. FARMER;HUAI GAO;WENXIN GU;JOSEPH M. KENNEDY;BRIAN LEDFORD;MARK W. LEDEBOER;FRANCOIS MALTAIS;EMANUELE PEROLA;TIANSHENG WANG
分类号 C07D471/04;A61K31/444;A61K31/506;A61P31/16 主分类号 C07D471/04
代理机构 代理人
主权项
地址