发明名称 |
NOVEL RHTB PROTEIN VARIANTS AND THE METHOD OF PRODUCING O-PHOSPHOSERINE USING THE SAME |
摘要 |
The present invention relates to an RhtB (homoserine/homoserine lactone export transporter) protein variant having an enhanced ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a polynucleotide encoding the protein, a vector comprising the polynucleotide, an OPS-producing microorganism comprising the protein variant, a method of producing O-phosphoserine using the microorganism, and a method for preparing cysteine or its derivatives, which comprises reacting O-phosphoserine, produced by the method above, with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism that expresses OPSS. |
申请公布号 |
US2016130310(A1) |
申请公布日期 |
2016.05.12 |
申请号 |
US201414890422 |
申请日期 |
2014.05.09 |
申请人 |
CJ CHEILJEDANG CORPORATION |
发明人 |
KIM Sol;KIM Hye Won;CHANG Jin Sook;YOO In Hwa |
分类号 |
C07K14/245;C12P13/12;C12P13/00 |
主分类号 |
C07K14/245 |
代理机构 |
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代理人 |
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主权项 |
1. An RhtB (homoserine/homoserine lactone export transporter) protein variant having enhanced O-phosphoserine (OPS) exporting activity. |
地址 |
Seoul KR |