| 主权项 |
1. A compound represented by the formula (I):or a pharmaceutically acceptable salt thereof, wherein:
a) R1 and A are each independently selected from: R1 is selected from: R11, where R11 is selected from:
1) Hydrogen;2) Deuterium;3) Cl-C8 alkyl;4) Substituted C1-C8 alkyl;5) C2-C8 alkenyl;6) Substituted C2-C8 alkenyl;7) C2-C8 alkynyl;8) Substituted C2-C8 alkynyl;9) C3-C12 cycloalkyl;10) Substituted C3-C12 cycloalkyl;11) Aryl;12) Substituted aryl;13) Heterocycloalkyl;14) Substituted heterocycloalkyl;15) Heteroaryl; and16) Substituted heteroaryl; b) —C(O)OR11, where R11 is as previously defined; c) —C(O) R11, where R11 is as previously defined; d) —C(O)OCH2-T-R12, where T is —O— or —S— and R12 is selected from:
1) C1-C8 alkyl;2) Substituted C1-C8 alkyl;3) C2-C8 alkenyl;4) Substituted C2-C8 alkenyl;5) C2-C8 alkynyl;6) Substituted C2-C8 alkynyl;7) C3-C12 cycloalkyl;8) Substituted C3-C12 cycloalkyl;9) Aryl;10) Substituted aryl;11) Heterocycloalkyl;12) Substituted heterocycloalkyl;13) Heteroaryl; or14) Substituted heteroaryl; e) —C(O)N(R13)(R14), where R13 and R14 are independently selected from R11 and R11is as previously defined or R13 and R14, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heterocycloalkyl; f) —C(O)SR11, where R11 is as previously defined; g) —C(S)OR11, where R11 is as previously defined; h) —C(O)OCH2OC(O) R12, where R12 is as previously defined; i) —C(S)S R11, where R11 is as previously defined; R2, is selected from: hydrogen or methyl; X is selected from the group of consisting of: O, S(O)m, wherein m=0, 1, or 2, and —N(R12)—, wherein R12 is R11, and R11 is as previously defined, or R12 and R1 are combined together with the N which attached to is substituted or unsubstituted heterocycloalkyl. |
