| 发明名称 |
CARCINOMA DIAGNOSIS AND TREATMENT, BASED ON ODC1 GENOTYPE |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for the preventative or curative treatment of colorectal cancer, familial adenomatous polyposis (FAP) or neuroblastoma.SOLUTION: A pharmaceutical composition comprises a composition comprising a first agent that inhibits ornithine decarboxylase (ODC), and a second agent that modulates the polyamine pathway to reduce overall polyamine content in a patient when combined with the first agent.SELECTED DRAWING: None |
| 申请公布号 |
JP2016074672(A) |
申请公布日期 |
2016.05.12 |
| 申请号 |
JP20150213116 |
申请日期 |
2015.10.29 |
| 申请人 |
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIV OF ARIZONA;REGENTS OF THE UNIV OF CALIFORNIA A CALIFORNIA CORP |
发明人 |
EUGENE GERNER;JASON ZELL;CHRISTINE MCLAREN;FRANK MEYSKENS;HODA ANTON-CULVER;PATRICIA A THOMPSON |
| 分类号 |
A61K45/06;A61P35/00;A61P43/00 |
主分类号 |
A61K45/06 |
| 代理机构 |
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