| 发明名称 |
METHOD FOR PREPARING DEUTERATED AROMATIC COMPOUNDS |
| 摘要 |
There is provided a method for deuterating an aromatic compound having aromatic hydrogens. The method includes the steps:
(a) providing a liquid composition including deuterium oxide having dissolved or dispersed therein the aromatic compound and a transition metal catalyst; and(b) heating the liquid composition at a temperature of 120° C. or greater, and a pressure of 50 psi or greater, for a period of 24 hours or less, to form a deuterated aromatic compound. |
| 申请公布号 |
US2016130194(A1) |
申请公布日期 |
2016.05.12 |
| 申请号 |
US201414534299 |
申请日期 |
2014.11.06 |
| 申请人 |
E I DU PONT DE NEMOURS AND COMPANY |
发明人 |
HOWARD, JR. MICHAEL HENRY;Bellon David P.;Dickson David P.;Merlo Jeffrey A. |
| 分类号 |
C07B59/00;C07D487/04 |
主分类号 |
C07B59/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for deuterating an aromatic compound having aromatic hydrogens, said method comprising:
(a) providing a liquid composition comprising deuterium oxide having dissolved or dispersed therein the aromatic compound and a transition metal catalyst; and (b) heating the liquid composition at a temperature of 120° C. or greater, and a pressure of 50 psi or greater, for a period of 24 hours or less, to form a deuterated aromatic compound;wherein (b) is carried out in an air atmosphere. |
| 地址 |
Wilmington DE US |
