COMPOUNDS FOR THE DIAGNOSIS OR TREATMENT OF DISORDERS ASSOCIATED WITH PROTEIN OR PEPTIDE OLIGOMERS
摘要
The present invention relates to compounds of Formula (I) as defined herein as well as conjugates comprising said compounds and pharmaceutical compositions comprising said compounds or conjugates. Also encompassed are methods for selectively detecting oligomeric proteins or peptides associated with a conformational disorder in a sample, and methods for diagnosing or treating a conformational disorder associated with protein or peptide oligomers in a subject.
申请公布号
WO2016073385(A1)
申请公布日期
2016.05.12
申请号
WO2015US58692
申请日期
2015.11.03
申请人
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;NATIONAL UNIVERSITY OF SINGAPORE;NEW YORK UNIVERSITY
发明人
CHANG, YOUNG-TAE;SU, DONGDONG;TEOH, CHAI LEAN;SAHU, SRIKANTA;WISNIEWSKI, THOMAS