| 主权项 |
1. A compound of Formula (IV): or a stereoisomer, or a mixture of stereoisomers, or a pharmaceutically acceptable salt thereof, wherein: J is C1-C4 alkyl or C3-C6 carbocyclyl, wherein the C1-C4 alkyl or C3-C6 carbocyclyl is optionally substituted with 1-4 halogen, —OH, aryl or cyano; {circle around (T)} is C3-C5 carbocyclylene that is attached to L and to the remainder of the compound of Formula IV through two adjacent carbons, wherein said C3-C5 carbocyclylene is optionally substituted with C1-C4 alkyl, C1-C3 haloalkyl, halogen, —OH, or cyano, or {circle around (T)} is C5-C8 bicyclic carbocyclylene that is attached to L and to the remainder of the compound of Formula IV through two adjacent carbons, or C3—C6 carbocyclylene that is attached to L and to the remainder of the compound of Formula IV through two adjacent carbons, wherein said C3—O6 carbocyclene is optionally substituted with C1-C4 alkyl or C1-C3 haloalkyl; L is C3-C6 alkylene, C3-C6 alkenylene or —(CH2)3-cyclopropylene-, optionally substituted with 1-4 halogen, —OH, or cyano; Q is C2-C4 alkyl or C3-C6 carbocyclyl optionally substituted with C1-C3 alkyl, halogen, —OH, or cyano; E is C1-C3 alkyl or C2-C3 alkenyl, optionally substituted with 1-3 halogen; W is H, —OH, —O(C1-C3)alkyl, —O(C1-C3)haloalkyl, halogen or cyano; and Z2a is H or C1-C3 alkyl. |
