发明名称 |
HIGH-AFFINITY IMMUNOPOLYMERS |
摘要 |
The present disclosure is directed to high-affinity immunopolymers for use in a variety of immunoassays and other techniques. The immunopolymers comprise a plurality of antibodies, a plurality of coupling proteins, and a plurality of detectable labels. The plurality of antibodies and plurality of coupling proteins are associated by a high-efficiency conjugation moiety, and may be used in highly multiplexed assays. Methods of preparing the high-affinity immunopolymers are provided. Also disclosed are methods of detecting an antigen that include reacting an antigen with a high-affinity immunopolymer of the disclosure. Reagent mixtures and methods for quantitative immunochemical assays are also provided. The mixtures and methods may include the high-affinity immunopolymers disclosed herein. |
申请公布号 |
WO2016073833(A1) |
申请公布日期 |
2016.05.12 |
申请号 |
WO2015US59424 |
申请日期 |
2015.11.06 |
申请人 |
CELL IDX, INC.;THE UNIVERSITY OF CHICAGO |
发明人 |
SCHWARTZ, DAVID A.;KRON, STEPHEN J.;FLOR, AMY C. |
分类号 |
A61K39/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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地址 |
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