发明名称 |
Methods for affinity maturation-based antibody optimization |
摘要 |
Provided herein is a rational method of affinity maturation to evolve the activity of an antibody or portion thereof based on the structure/affinity or activity relationship of an 5 antibody. The resulting affinity matured antibodies exhibit improved or optimized binding affinity for a target antigen. |
申请公布号 |
AU2016202532(A1) |
申请公布日期 |
2016.05.12 |
申请号 |
AU20160202532 |
申请日期 |
2016.04.21 |
申请人 |
FABRUS LLC |
发明人 |
SMIDER, VAUGHN;MAO, HELEN HONGYUAN |
分类号 |
C07K16/00;C07K16/28 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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