发明名称 |
Methods of using SPECT/CT analysis for staging cancer |
摘要 |
A method of evaluating a subject suspected of harboring a prostrate tumor includes administering to the subject an effective amount of a gamma-emitting transition metal complex conjugated to a targeting moiety that selectively binds to prostate-specific membrane antigen (PSMA), including PSMA expressed on the surface of a prostate tumor; subjecting the subject to a nuclear medicine tomographic imaging technique to obtain one or more images of at least a portion of prostate tissue that comprises tumor lesions; assessing a level of uptake of said gamma-emitting transition metal complex conjugated to a targeting moiety by said at least a portion of prostate tissue compared to a level of uptake by control tissue; and determining if a ratio of the level of uptake by said at least a portion of prostate tissue compared the level of uptake by control tissue is at or above a predetermined threshold. |
申请公布号 |
AU2014337055(A1) |
申请公布日期 |
2016.05.12 |
申请号 |
AU20140337055 |
申请日期 |
2014.10.17 |
申请人 |
MOLECULAR INSIGHT PHARMACEUTICALS, INC. |
发明人 |
ARMOR, THOMAS |
分类号 |
A61K51/00;A01N59/16;A61K51/04 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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