发明名称 |
COMPOSICION FARMACEUTICA PARA EL TRATAMIENTO Y/O PREVENCION DEENFERMEDADES RETINIANAS DEGENERATIVAS |
摘要 |
The invention relates to a composition comprising mesenchymal stem cells (MSCs), preferably originating from adipose tissue (AD-MSCs), combined with vasoactive intestinal peptide (VIP) and nicotinamide (NIC) and, more preferably, also combined with retinoic acid (ATRA) and with supernatant of a cell culture of retinal pigment epithelium (RPE). The invention also relates to the use of this composition for the treatment and/or prevention of retinal damage, preferably degenerative diseases of the retina, for example, but not limited to, degenerative diseases of the RPE, of the photoreceptors and of the neuroretina. |
申请公布号 |
ES2539329(B1) |
申请公布日期 |
2016.05.12 |
申请号 |
ES20130031743 |
申请日期 |
2013.11.29 |
申请人 |
UNIVERSIDAD DE VALLADOLID |
发明人 |
SINGH, AMAR KUMAR;SRIVASTAVA, GIRISH KUMAR;FERNANDEZ BUENO, IVAN;GAYOSO RODRIGUEZ, MANUEL JOSE;PASTOR JIMENO, JOSE CARLOS |
分类号 |
C12N5/0775;A61K31/203;A61K31/465;A61K35/44;A61K38/17;A61P27/02 |
主分类号 |
C12N5/0775 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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