| 摘要 |
Reinforced engineered biomaterials, and methods of making them, may be useful to form engineered leathers. Such engineered hides may be reinforced by encapsulating, and/or cross-linking to, a mesh and/or scaffold material, which may be a synthetic polymeric material. The resulting hide may include a stratified structure in which the mesh is held between layers of collagen-dense regions, where the collagen-dense regions overlaying the mesh following the contour of the mesh. Alternatively or additionally, the resulting hide may be a composite of a fibrous matrix that has been tanned to allow crosslinking of the fibrous matrix to the collagen formed by cultured cells. These engineered leathers may be referred to as fiber-reinforced biological tissue composites. The resulting materials may have superior durability and flexibility compared to other engineered materials and native leather, while retaining the look and feel of native leather. |
