| 发明名称 |
SIGNAL CONFINEMENT SEQUENCING (SCS) AND NUCLEOTIDE ANALOGUES FOR SIGNAL CONFINEMENT SEQUENCING |
| 摘要 |
Novel fluorescent nucleotide analogues are provided herein. Also provided herein are methods of using the nucleotide analogues in sequencing-by-synthesis and signal confinement methods. |
| 申请公布号 |
US2016130647(A1) |
申请公布日期 |
2016.05.12 |
| 申请号 |
US201514921466 |
申请日期 |
2015.10.23 |
| 申请人 |
Complete Genomics, Inc. |
发明人 |
Drmanac Snezana;Li Handong;Drmanac Radoje;Harness Eric;Xu Chongjun |
| 分类号 |
C12Q1/68;C07H19/10;C07H19/207 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A nucleotide analogue of the following formula:wherein
n is 0, 1, 2, 3, 4, 5, 6, or 7; L is absent or a linking group; R1 is a nucleoside base; R2 is hydrogen or a blocking group; B is a binding molecule; and X is a detection label. |
| 地址 |
Mountain View CA US |
