| 发明名称 |
THERAPEUTIC COMBINATIONS COMPRISING ANTI-CD73 ANTIBODIES AND USES THEREOF |
| 摘要 |
The present invention provides therapeutic combinations featuring anti-CD73 antibodies (e.g., MEDI9447) and A2A receptor inhibitors and methods of using such combinations for reducing tumor-mediated immunosuppression. |
| 申请公布号 |
US2016129108(A1) |
申请公布日期 |
2016.05.12 |
| 申请号 |
US201514937565 |
申请日期 |
2015.11.10 |
| 申请人 |
MedImmune Limited |
发明人 |
SACHSENMEIER Kris;Sult Erin;Hay Carl;Poon Edmund |
| 分类号 |
A61K39/395;A61K31/519 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of inhibiting tumor growth in a subject comprising administering an anti-CD73 antibody, or an antigen-binding fragment thereof, and an A2A receptor inhibitor for inhibiting tumor growth to the subject. |
| 地址 |
Cambridge GB |
