ANTI-ANG2 ANTIBODIES AND METHODS OF USE THEREOF

摘要

The invention provides anti-Ang2 antibodies, including dual-specific antibodies that specifically bind Ang2 and VEGF, and methods of using the same for treatment of pathological disorders associated with angiogenesis. The invention also provides methods of identifying improved antibody variants (e.g., with enhanced binding affinity, expression, and/or stability).