| 发明名称 |
SHIP INHIBITION TO COMBAT OBESITY |
| 摘要 |
The present invention relates to the use of SHIP1 inhibitors and pan-SHIP1/2 inhibitors in various methods, including, without limitation: (i) a method to treat obesity or reduce body fat of an obese subject; (ii) a method to limit bone development in a subject suffering from an osteopetrotic or sclerotic disease; (iii) a method to treat or prevent diabetes; (iv) a method to reduce glucose intolerance or insulin resistance; and (v) a method to lower cholesterol. |
| 申请公布号 |
US2016129017(A1) |
申请公布日期 |
2016.05.12 |
| 申请号 |
US201414900719 |
申请日期 |
2014.07.01 |
| 申请人 |
KERR William G.;IYER Sonia;THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY NEW YORK |
发明人 |
KERR William G.;IYER Sonia |
| 分类号 |
A61K31/575;A61K31/568;A61K31/4709;A61K31/5685;A61K31/473;A61K31/4045;C12N15/113;A61K31/655 |
主分类号 |
A61K31/575 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method to treat obesity or reduce body fat of an obese subject, said method comprising:
administering a SHIP1 inhibitor or a pan-SHIP1/2 inhibitor to an obese subject in an amount effective to treat obesity or reduce body fat of the obese subject. |
| 地址 |
Syracuse NY US |
