MULTI-(AMINO ACID) POLYMER-HYDROXYAPATITE BONE REPAIR MATERIAL, SUPPORTING-TYPE IMPLANT AND PREPARATION METHOD

摘要

A multi-(amino acid) polymer-hydroxyapatite bone repair material, a supporting-type implant and a preparation method. The repair material is formed by a multi-(amino acid) polymer consisting of ε-aminocaproic acid and other α-amino acids and a modified hydroxyapatite component. For the modified hydroxyapatite component, a medically acceptable calcium salt having a solubility higher than that of hydroxyapatite is used as a modifying component and forms, together with hydroxyapatite, the modified hydroxyapatite; the mass ratio of the calcium salt as the modifying component to the hydroxyapatite is (2-20):(98-80), and the modified hydroxyapatite accounts for 10-70% of the mass of the bone repair material; and the ε-aminocaproic acid in the multi-(amino acid) polymer accounts for 60-99% of the total molar weight of the multi-(amino acid) polymer. Micro-degradation can occur on the surface of the supporting-type implant prepared from the repair material under the action of interstitial fluid, massive calcium/phosphor ions can be quickly released, so that quick healing of bone tissues can be quickly promoted, enough mechanical strength can be stably maintained, and basic requirement for mechanical support in the tissue healing process can be met.