摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for producing a 1,3-disubstituted pyrazole-4-carboxylic acid ester having little discoloration. <P>SOLUTION: The method for producing a pyrazole compound represented by general formula (5) (R<SP POS="POST">1</SP>and R<SP POS="POST">4</SP>are each independently alkyl; and R<SP POS="POST">5</SP>is alkyl or aryl) includes reacting an ester 2-acyl-3-aminoacrylate represented by general formula (1) (R<SP POS="POST">1</SP>, R<SP POS="POST">2</SP>, R<SP POS="POST">3</SP>and R<SP POS="POST">4</SP>are each independently alkyl) with an alkylhydrazine or an arylhydrazine in the presence of a base. <P>COPYRIGHT: (C)2013,JPO&INPIT |