发明名称 |
PYRROLO-PYRROLE CARBAMATE AND RELATED ORGANIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF |
摘要 |
The invention provides pyrrolo-pyrrole carbamate and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., solid tumor cancer, obesity, Down's syndrome, Alzheimer's disease, or pain, in a patient. The octahydropyrrolo pyrrole carbamates could be derived from hexafluoroisopropanol, N,N-disuccinimide and such. The activity of carbamates in MAGL, FAAH, and ABHD6 assays are also described. |
申请公布号 |
EP3016653(A1) |
申请公布日期 |
2016.05.11 |
申请号 |
EP20140820480 |
申请日期 |
2014.07.01 |
申请人 |
ABIDE THERAPEUTICS, INC. |
发明人 |
JONES, TODD, K.;CISAR, JUSTIN, S.;GRICE, CHERYL, A.;WANG, DONG-HUI;WEBER, OLIVIA, D. |
分类号 |
A61K31/407;C07D487/04;C07D519/00 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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