发明名称 免疫抑制性細胞捕集材及び免疫抑制性細胞捕集用カラム
摘要 This invention discloses an immunosuppressive cell-capturing material comprising a molded body that includes: a readily hydrolyzable condensation polymer having an amino group; a poorly hydrolyzable polymer coating the readily hydrolyzable condensation polymer; and a ligand-conjugated poorly hydrolyzable polymer coating the poorly hydrolyzable polymer, wherein the ligand is at least one selected from the group consisting of a NH2 group, a secondary amino group, a tertiary amino group, a polyamine residue, a basic cyclic polypeptide residue, an aminoglycosidic compound residue, chloroquine, primaquine, mefloquine, imiquimod, and nystatin, and wherein the content of the amino group in the molded body is 150 μmol/g or less. The invention also discloses an immunosuppressive cell-capturing column filled with the capturing material.
申请公布号 JP5916712(B2) 申请公布日期 2016.05.11
申请号 JP20130507607 申请日期 2012.03.27
申请人 国立大学法人滋賀医科大学 发明人 小笠原 一誠;寺本 和雄;上田 祐二;伊藤 靖;石垣 宏仁
分类号 A61M1/36;A61K35/17;A61P35/00;B01J20/22;B01J20/24;B01J20/281 主分类号 A61M1/36
代理机构 代理人
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