发明名称 |
A PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER |
摘要 |
The present invention relates to a combination comprising a substance with inhibiting effect on the ileal bile acid transport system (I BAT) and at least one other active substance selected from an IBAT inhibitor; an enteroendocrine peptide or enhancer thereof; a dipeptidyl peptidase-IV inhibitor; a biguanidine; an incretin mimetic; a thiazolidinone; a PPAR agonist; a HMG Co-A reductase inhibitor; a bile acid binder; and a TGR5 receptor modulator; wherein the IBAT inhibitor compound and the at least one other active substance are administered simultaneously, sequentially or separately. |
申请公布号 |
EP2637646(B1) |
申请公布日期 |
2016.05.11 |
申请号 |
EP20110840481 |
申请日期 |
2011.11.08 |
申请人 |
ALBIREO AB |
发明人 |
GILLBERG, PER-GÖRAN;GRAFFNER, HANS;STARKE, INGEMAR |
分类号 |
A61K9/52;A61K31/554;A61K31/785;A61P1/12;A61P1/16;A61P3/00 |
主分类号 |
A61K9/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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