Method for treating psoriasis

摘要

The present invention provides a pharmaceutical composition for treating an autoimmune disease comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the composition is to be administered to a subject in a dose of the agent from 0.2 mg to 30 mg.

主权项

1. A method for treating an autoimmune disease comprising administering to a subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein said administering comprises administering said composition to the subject intravenously in a dose of the agent of from 0.3 mg to 5 mg, weekly, every two weeks, every four weeks, or every calendar month, wherein the agent is a humanized anti-CD4 antibody comprising an IgG1 constant domain, an H chain V domain comprising SEQ ID NO: 1 and an L chain V domain comprising SEQ ID NO: 2, and wherein the autoimmune disease is psoriasis.