发明名称 |
Tc-99m produced by proton irradiation of a fluid target system |
摘要 |
Methods for producing Tc-99m radioisotope by proton irradiation of a fluid target matrix. A method of producing Tc-99m includes irradiating a fluid target matrix comprising Mo-100 with a proton beam to transform at least a portion of Mo-100 to Tc-99m. Optionally, the fluid target matrix further includes at least one of O-18, O-16, or N-14, which upon exposure to the proton beam concurrently transform at least a portion of O-18 to F-18, at least a portion of O-16 to N-13, at least a portion of the O-16 to O-15, or at least a portion of N-14 to C-11. The method further includes isolating Tc-99m and optionally at least one of F-18, N-13, O-15, or C-11 from the irradiated fluid target matrix. An additional source of Tc-99m is available from the decay of Mo-99 that is co-produced from the Mo-100 during irradiation with the proton beam. |
申请公布号 |
US9336916(B2) |
申请公布日期 |
2016.05.10 |
申请号 |
US201113106634 |
申请日期 |
2011.05.12 |
申请人 |
TcNet, LLC |
发明人 |
Stevenson Nigel R. |
分类号 |
G21G1/10;G21G1/00 |
主分类号 |
G21G1/10 |
代理机构 |
Wood, Herron & Evans, LLP |
代理人 |
Wood, Herron & Evans, LLP |
主权项 |
1. A method of producing Tc-99m, the method comprising:
irradiating a fluid target matrix comprising Mo-100 with a proton beam to directly transform at least a portion of Mo-100 to Tc-99m via a Mo-100(p,2n)Tc-99m reaction and provide an irradiated fluid target matrix; and isolating Tc-99m from the irradiated fluid target matrix. |
地址 |
Bridgewater NJ US |