发明名称 |
Virus causing respiratory tract illness in susceptible mammals |
摘要 |
The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof. |
申请公布号 |
US9334543(B2) |
申请公布日期 |
2016.05.10 |
申请号 |
US201414553957 |
申请日期 |
2014.11.25 |
申请人 |
Erasmus University Medical Center Rotterdam |
发明人 |
De Jong Jan Cornelius;Fouchier Ronaldus Adrianus Maria;Van Den Hoogen Bernadetta Gerarda;Osterhaus Albertus D M E;Groen Jan |
分类号 |
C12Q1/70;C12Q1/68;C07K14/005;C12N7/00;C12N15/86;A61K39/00 |
主分类号 |
C12Q1/70 |
代理机构 |
TraskBritt, P.C. |
代理人 |
TraskBritt, P.C. |
主权项 |
1. A method for diagnosing a human metapneumovirus infection in a mammal, the method comprising:
determining in a sample from the mammal the presence of a component of human metapneumovirus by hybridizing a nucleic acid amplification product of the sample with a DNA molecule of at least 10 nucleotides in length that is at least 90% identical to a stretch of the DNA sequence of SEQ ID NO: 36, or the complement thereof, wherein the nucleic acid amplification product is the product of a nucleic acid amplification reaction with a nucleic acid from the sample as the template for the reaction; wherein hybridization of the DNA molecule with the nucleic acid amplification product indicates human metaPneumovirus infection of the mammal; and wherein the nucleic acid amplification product comprises DNA. |
地址 |
Rotterdam NL |