Ureter to ileal conduit anastomosis using magnetic compression and related delivery devices and methods

摘要

Magnetic compression anastomosis can be carried out by placing cooperating magnets, one in the ileal conduit and one in the ureter, to lock together and form the anastomosis. The magnets may be placed to form a side-to-side anastomosis. At least one of the magnets can include radioactive material. Catheters may be used to place the magnets, and the catheters may have at least one deflatable or retractable tissue spacer.

主权项

1. A ureter catheter, comprising:
a catheter body sized and configured to travel through a ureter of a patient, the catheter body having an inner channel and an outer wall enclosing the inner channel, wherein the catheter body comprises at least one inflatable tissue spacer proximate a magnet exit window, wherein the magnet exit window is an open space in the outer wall of the catheter body that is spaced apart from a tip of the catheter body, the at least one inflatable tissue spacer having an inflated configuration during intrabody placement of the catheter body, wherein the at least one inflatable tissue spacer is disposed on and extends laterally outward from the outer wall of the catheter body, the at least one inflatable tissue spacer is affixed to the catheter body to reside at a fixed longitudinal position relative to the catheter body while being able to laterally expand and retract; and a first rare earth magnet releasably held in the catheter body adapted for positioning in a distal end of the ureter proximate an ileal conduit, wherein the first rare earth magnet is elongate and has a length dimension that is greater than a width dimension or radius and is releasably held in the inner channel of the catheter body separate from the at least one tissue spacer to exit from the magnet exit window after the at least one inflatable tissue spacer is at least partially deflated to position the magnet exit window adjacent the ileal conduit and closer to target tissue of the ileal conduit than when the at least one tissue spacer is in the inflated configuration, and wherein, in position in the distal end of the patient ureter, the first rare earth magnet is configured to cooperate with a second rare earth magnet on an opposing side of the target tissue to form a linear compression anastomosis.