发明名称 |
Method for preparing functionalized lipid capsules |
摘要 |
The present invention relates to a liquid lipid core/solid lipid shell capsule surface-functionalized with at least one compound containing at least one amino function, characterized in that the lipid core/lipid shell architecture is on the nanometric scale and in that said compound is covalently bonded to said solid lipid shell via a transacylation reaction. It also relates to a method for preparing such capsules. |
申请公布号 |
US9333181(B2) |
申请公布日期 |
2016.05.10 |
申请号 |
US201013260168 |
申请日期 |
2010.03.30 |
申请人 |
UNIVERSITE D'ANGERS;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
Benoit Jean-Pierre;Perrier Thomas |
分类号 |
A61K9/20;A61K9/51;A23L1/00;A23L1/30;A61K8/11;A61K8/60;A61K8/64;A61K47/48;A61Q19/00 |
主分类号 |
A61K9/20 |
代理机构 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
代理人 |
Oblon, McClelland, Maier & Neustadt, L.L.P. |
主权项 |
1. A capsule, comprising:
a liquid lipid core; and a solid lipid shell surface-functionalized with at least one compound (a) comprising at least one amine functional group wherein a shell architecture of the liquid lipid core and the solid lipid shell is on the nanometric scale, and wherein the at least one compound (a) is covalently bonded to a surface of the solid lipid shell via a transacylation reaction. |
地址 |
Angers FR |