Differentiating ES cells using a tenascin

摘要

The invention relates to assays for screening growth factors, adhesion molecules, immunostimulatory molecules, extracellular matrix components and other materials, alone or in combination, simultaneously or temporally, for the ability to induce directed differentiation of pluripotent and multipotent stem cells.

主权项

1. A method for inducing differentiation of an embryonic stem (ES) cell to form differentiated cells selected from the group consisting of cells of endothelial lineage, and cells of endodermal lineage, the method comprising exposing the ES cell to a tenascin, thereby inducing differentiation of the ES cell.