发明名称 |
GASTRORETENTIVE GEL FORMULATIONS |
摘要 |
The present invention provides a gastric retentive gel composition comprising : (a) a hydrophobic or amphiphilic liquid gelled with an organogelator; (b) an active agent; and (c) a hard wax or wax-like additive, for controlled delivery of the active agent to or through the upper gastrointestinal tract, in particular to or through the stomach. The gel composition forms a stable, floating and coherent raft in the gastric environment, and is not directly expelled from the stomach as a result of gastric emptying. The active agent is released from the composition in a controlled manner for absorption or local action. |
申请公布号 |
WO2016066256(A1) |
申请公布日期 |
2016.05.06 |
申请号 |
WO2015EP02117 |
申请日期 |
2015.10.26 |
申请人 |
JAGOTEC AG |
发明人 |
VERGNAULT, GUY;CONTE, UBALDO;MAGGI, LAURETTA |
分类号 |
A61K9/06;A61K47/14;A61K47/38;A61K47/44 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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