发明名称 |
Vial preparation method and system |
摘要 |
Embodiments generally relate to vial preparation methods and to vials prepared by such methods. Some embodiments relate to use of an apparatus, such as a lyophilisation apparatus, to perform the methods. An illustrative vial preparation method comprises: housing a plurality of vials in a temperature-controlled environment, wherein the plurality of vials each have a volume of a substance therein and each defines an unfilled volume therein, each vial having a stopper partially inserted into an opening of the vial so that gas can transfer between the unfilled volume and an external volume; applying a vacuum to the environment to reduce pressure in the environment and in the unfilled volume of each vial to a first pressure level; venting an inert gas into the environment to raise the pressure in the environment and in the unfilled volume of each vial to a second pressure level; allowing the vials to rest in the environment at the second pressure level for a predetermined period; repeating the applying, venting and allowing at least once; and fully inserting the stopper into each opening to seal each vial after the repeating. |
申请公布号 |
AU2011286179(B2) |
申请公布日期 |
2016.05.05 |
申请号 |
AU20110286179 |
申请日期 |
2011.08.05 |
申请人 |
HOSPIRA AUSTRALIA PTY LTD |
发明人 |
WENSLEY, EMMA J.;KNILL, ANDREW MALCOLM;SUENDERMANN, JOHN FREDRIC |
分类号 |
B65B31/02;B65D47/32 |
主分类号 |
B65B31/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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