OPIOID DETECTION BASED ON HIGH QUALITY GRAPHENE TRANSISTOR ARRAYS AND A SYNTHETIC MU RECEPTOR

摘要

The present invention provides methods for fabricating field-effect devices and sensor arrays. The field of the invention also pertains to methods of using the sensors individually, in combination, and in array fashion to detect molecules. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.

主权项

1. A method of detecting the presence of an analyte and/or determining analyte concentration in a sample, comprising:
applying a voltage to a graphene field effect transistor sensor having a conduction channel and comprising a detection molecule being bound by an amide bond to the graphene; measuring a current of the sensor; exposing the conduction channel to the sample; measuring the current of the sensor; determining the presence and/or concentration of the analyte based upon a difference in the current; and determining the conformational changes of the receptor upon analyte binding.